Injectable hydrogels for cartilage and bone tissue engineering
نویسندگان
چکیده
منابع مشابه
Hydrogels Containing Marine Polysaccharides For Bone and Cartilage Tissue Engineering
Introduction: The most common biopolymers used to build-up 3D scaffolds for bone and cartilage tissue engineering are chitosan, alginate, cellulose derivatives, hyaluronic acid, chondroitin sulfate, collagen and gelatin. In this study, we propose to evaluate the potential of two new marine exopolysaccharides (HE800 and GY785) that are glycosaminoglycan-like polymers and that can be produced in ...
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Hydrogels have many different applications in the field of regenerative medicine. Biodegradable, injectable hydrogels could be utilized as delivery systems, cell carriers, and scaffolds for tissue engineering. Injectable hydrogels are an appealing scaffold because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, ...
متن کاملAn in vitro study of two GAG-like marine polysaccharides incorporated into injectable hydrogels for bone and cartilage tissue engineering.
Natural polysaccharides are attractive compounds with which to build scaffolds for bone and cartilage tissue engineering. Here we tested two non-standard ones, HE800 and GY785, for the two-dimensional (2-D) and three-dimensional (3-D) culture of osteoblasts (MC3T3-E1) and chondrocytes (C28/I2). These two glycosaminoglycan-like marine exopolysaccharides were incorporated into an injectable silyl...
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Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential for use in biomedical applications. Their extracellular matrix-like features have been key factors for their choice as vehicles for cell delivery strategies aimed at tissue regeneration. A variety of strategies to decorate them with biofunctional moieties and to modulate their biophysical properties have...
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Degradable and injectable hydrogels may be ideal for bone-tissue engineering, especially in the craniofacial region because of the ease of access for injection. Alginate hydrogels potentially could be used as injectable cell delivery vehicles, but they exhibit a limited range of mechanical properties and uncontrollable disintegration time. Therefore we synthesized new hydrogels, composed of pol...
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ژورنال
عنوان ژورنال: Bone Research
سال: 2017
ISSN: 2095-6231
DOI: 10.1038/boneres.2017.14